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Dott. Federico MUSSANO

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Temi di ricerca

 

Il dott. Federico Mussano svolge attività di ricerca odontoiatrica di base prevalentemente in due ambiti:

-la biologia delle cellule staminali mesenchimali (Adipose derived Stem Cells, ASC e bone marrow derived Mesenchymal Stem Cells, MSC) come fonte per la rigenerazione di tessuto osseo e nell'eziopatogenesi dell'osteoradionecrosi (in collaborazione con il Molecular Biotechnology Center dell'Università di Torino);

-l'adozione di tecnologie di ricoprimento a film sottile inorganico per la modificazione delle qualità superficiali dei materiali bulk di sostrato (in collaborazione con il Politecnico di Torino) quali protesi orali, onde ridurre l'adesione batterica superficiale, e impianti in titanio endo-ossei per l'accelarazione dell'osseointegrazione.

 

Educational and professional background

2004                      DDS at the University of Turin

2009                      PhD in Dental Materials at the University of Turin

2008-2009             Visiting Scientist at the Weintraub Center of the UCLA School of Dentistry and Researcher at the Regenerative Bioengineering and Repair Lab at the David Geffen School of Medicine of the UCLA.

Federico Mussano is Assistant Professor at the School of Dentistry of the University of Turin. 

 

Further notes

Federico Mussano

-was awarded with Optime Prize for merits in studies given by the Italian Industrial Union (Unione Industriale) thus becoming a permanent member of the "Optime Club".

-is Alumnus of the Weintraub Center for Reconstructive Biotechnology (http://www.weintraub.dent.ucla.edu/people/index.html)

-is Editor of Current Research in Dentistry (since 1st October 2014)

Current Research in Dentistry

 

Research Activities:

Bone physiology and biomaterials

 

Publications on Interantional Journals with Impact Factor:

 

  1. Canullo L, Genova T, Wang HL, Carossa S, Mussano F. Atmospheric-pressure dielectric-barrier-discharge plasma of Argon influences cell attachment and bacterial decontamination: in vitro preliminary results. Int J Oral Maxillofac Implants. 2017;32:1315-23.
  2. Mussano F, Genova T, Verga Falzacappa E, Scopece P, Munaron L, Rivolo P, Mandracci P, Benedetti A, Carossa S, Patelli A. In vitro characterization of two different atmospheric plasma jet chemical functionalizations of titanium surfaces Appl Surf Sci 2017; 409:314-24
  3. Mussano F, Genova T, Corsalini M, Schierano G, Pettini F, Di Venere D, Carossa S. Cytokine, Chemokine, and Growth Factor Profile Characterization of Undifferentiated and Osteoinduced Human Adipose-Derived Stem Cells. Stem Cells Int. 2017; 2017: 6202783. OPEN ACCESS https://doi.org/10.1155/2017/6202783.
  4. Mussano F, Genova T, Rivolo P, Mandracci P, Munaron L, Faga MG, Carossa S. Role of surface finishing on the in vitro biological properties of a silicon nitride-titanium nitride (Si3N4-TiN) compositeJ Mater Science 2017; 52(1):467-77.
  5. Canullo L, Genova T, Mandracci P, Mussano F, Abundo R, Fiorellini JP. Morphometric Changes Induced by Cold Argon Plasma Treatment on Osteoblasts Grown on Different Dental Implant Surfaces. Int J Periodontics Restorative Dent 2017; 37(4):541-548.
  6. Mandracci P, Mussano F, Rivolo P, Carossa S. Surface Treatments and Functional Coatings for Biocompatibility Improvement and Bacterial Adhesion Reduction in Dental Implantology. Coatings 2016, 6(1), 7; OPEN ACCESS doi:10.3390/coatings6010007
  7. Canullo L, Genova T, Tallarico M, Gautier G, Mussano F, Botticelli D. Plasma of Argon Affects the Earliest Biological Response of Different Implant Surfaces: An In Vitro Comparative Study. J Dent Res 2016; 95:566-73.
  8. Mussano F, Genova T, Munaron L, Petrillo S, Erovigni F, Carossa S. Cytokine, chemokine and growth factor profile of Platelet Rich Plasma. Platelets 2016; 7:1-5.
  9. Genova T, Munaron L, Carossa S, Mussano F. Overcoming physical constraints in bone engineering: 'the importance of being vascularized'. J Biomater Appl 2016; 30:940-51.
  10. Duraccio D, Mussano F, Faga MG. Biomaterials for dental implants: current and future trends. J Mater Science 2015; 50:4779-4812.
  11. Mandracci P, Mussano F, Ceruti P, Pirri CF, Carossa S. Reduction of bacterial adhesion on dental composite resins by silicon-oxygen thin film coatings. Biomed Mater 2015; 10:015017.
  12. Ceruti P, Asioli S, Mussano F, Righi A, Baldi I, Schierano G, Cassoni P, Carossa S. Transglutaminase-2 may be associated with peri-implant gingival overgrowth: preliminary assessments. Int J Prosthodont 2015; 28:615-620.
  13. Schierano G, Mussano F, Faga MG, Menicucci G, Manzella C, Sabione C, Genova T, Mauthe von Degerfeld M, Peirone B, Cassenti A, Cassoni P, Carossa S. An Alumina toughened Zirconia composite for dental implant application: in vivo animal results. Biomed Res Int 2015:157360. OPEN ACCESS http://dx.doi.org/10.1155/2015/157360
  14. Mussano F, Bartorelli Cusani A, Brossa A, Carossa S, Bussolati G, Bussolati B. Presence of osteoinductive factors in bovine colostrum. Biosci Biotechnol Biochem 2014;78:662-671.
  15. Vallée A, Faga MG, Mussano F, Catalano F, Tolosano E, Carossa S, Altruda F, Martra G. Alumina-zirconia composites functionalized with laminin-1 and laminin-5 for dentistry: Effect of protein adsorption on cellular response. Colloids Surf B Biointerfaces 2014;114:284-293.
  16. Honda Y, Ding X, Mussano F, Wiberg A, Ho CM, Nishimura I. Guiding the osteogenic fate of mouse and human mesenchymal stem cells through feedback system control. Sci Rep 2013;3:3420 DOI:10.1038/srep03420. OPEN ACCESS  http://www.nature.com/articles/srep03420
  17. Sacerdote P, Mussano F, Franchi S, Panerai AE, Bussolati G, Carossa S, Bartorelli A, Bussolati B. Biological components in a standardized derivative of bovine colostrum. J Dairy Sci 2013;96:1745-1754.
  18. Menicucci G, Mussano F, Schierano G, Rizzatti A, Aimetti M, Gassino G, Traini T, Carossa S. Healing properties of implants inserted concomitantly with anorganic bovine bone. A histomorphometric human study. Aust Dent J 2013;58:57-66.
  19. Mussano F, Rovasio S, Schierano G, Baldi I, Carossa S. The effect of glycine powdered air-flow and hand instrumentation on peri-implant soft tissues: a split-mouth pilot study. Int J Prosthodont 2013;26:42-44.
  20. Mozzati M, Arata V, Gallesio G, Mussano F, Carossa S. Immediate postextraction implant placement with immediate loading for maxillary full-arch rehabilitation: A two-year retrospective analysis. JADA 2012;143:124-133.
  21. Mozzati M, Arata V, Gallesio G, Mussano F, Carossa S. Immediate post-extractive dental implant placement with immediate loading on four implants for mandibular-full-arch rehabilitation: a retrospective analysis. Clin Implant Dent Relat Res 2013;15:332-340.
  22. Gazia R, Mandracci P, Mussano F, Carossa S. AlNx and a-SiOx coatings with corrosion resistance properties for dental implants. Surf Coat Technol 2011;206:1109-1115.
  23. Mengatto CM, Mussano F, Honda Y, Colwell CS, Nishimura I. Circadian Rhythm and Cartilage Extracellular Matrix Genes in Osseointegration: A Genome-Wide Screening of Implant Failure by Vitamin D Deficiency. PLoS One 2011;6:e15848. OPEN ACCESS http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0015848 
  24. Zuk P, Chou YF, Mussano F, Benhaim P, Wu BM. Adipose-derived stem cells and BMP2: Part 2. BMP2 may not influence the osteogenic fate of human adipose-derived stem cells. Connect Tissue Res 2011;52:119-32.
  25. Mussano F, Lee KJ, Tran L, Zuk P, Cacalano NA, Jewett A, Carossa S, Nishimura I. Differential effect of ionizing radiation exposure on multipotent and differentiation-restricted bone marrow mesenchymal stem cells. J Cell Biochem 2010;111:322-32.
  26. Mandracci P, Ceruti P, Ricciardi C, Mussano F, Carossa S. a-SiOx Coatings Grown on Dental Materials by PECVD: Compositional Analysis and Preliminary Investigation of Biocompatibility Improvements. Chem Vapor Deposition 2010;16:29-34.
  27. Mandracci P, Mussano F, Ricciardi C, Ceruti P, Pirri CF, Carossa S. Low temperature growth of thin film coatings for the surface modification of dental prostheses. Surf Coat Technol 2008;202:2477-2481.
  28. Rizzatti A, Ceruti P, Mussano F, Erovigni F, Preti G. A new clinical method for evaluating the closest speaking space in dentulous and edentulous subjects: a pilot study. Int J Prosthodont 2007;20:259-262.
  29. Mussano F, Ciccone G, Ceccarelli M, Baldi I, Bassi F. Bone morphogenetic proteins and bone defects: a systematic review. Spine 2007;32:824-830.
  30. Ceruti P, Menicucci G, Schierano G, Mussano F, Preti G. Mandibular implant-retained overdentures with 2 different prosthetic designs: a retrospective pilot study on maintenance interventions. Int J Prosthodont 2006;19:557-559.

 Publications on Interantional Open Access Journals:

Bisaro B, Mussano F, Mattia S, Marmotti A, Forni M, Zanini C. Human Umbilical Cord-Derived Mesenchymal Stem Cells As A Source Of Odontoblasts: A GMP-compliant ApproachJournal Of Evolving Stem Cell Research. Vol: 1, Issue 1

http://oap-journals.org/jesr/article/412

Chapters in Interantional Books:

Mussano F, Genova T, Guastella S, Faga MG, Carossa S. Possible Role of Microcrystallinity on Surface Properties  of Titanium Surfaces for Biomedical Application, In: Crystalline and Non-crystalline Solids, edited by Pietro Mandracci, ISBN 978-953-51-2446-7, Print ISBN 978-953-51-2445-0, Published: June 29, 2016 under CC BY 3.0 license.

OPEN ACCESS LINK:

http://www.intechopen.com/articles/show/title/possible-role-of-microcrystallinity-on-surface-properties-of-titanium-surfaces-for-biomedical-applic.

 

Mussano F, Genova T, Munaron L, Faga MG, Carossa S. Ceramic Biomaterials for Dental Implants: Current Use and Future Perspectives, In: Dental Implantology and biomaterial, edited by Mazen Ahmad Jawad Amin Almasri, ISBN 978-953-51-2522-8, Print ISBN 978-953-51-2521-1, Published: August 17, 2016 under CC BY 3.0 license. 

OPEN ACCESS LINK:

 http://www.intechopen.com/articles/show/title/ceramic-biomaterials-for-dental-implants-current-use-and-future-perspectives. 

 

Mandracci P, Gazia R, Mussano F, Carossa S, Pirri CF. Si-Based Amorphous Thin Films for the Performance Improvement of Dental Prostheses and Implants, In: Prostheses: Design, Types and Complications, Colombo DF, Rossi GS, Nova Science Publishers, 2012, pages from 67 to 82, ISBN: 9781621008545

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